Review



bax channel blocker  (Santa Cruz Biotechnology)


Bioz Verified Symbol Santa Cruz Biotechnology is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 92
      Buy from Supplier

    Structured Review

    Santa Cruz Biotechnology bax channel blocker
    Bax Channel Blocker, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bax channel blocker/product/Santa Cruz Biotechnology
    Average 92 stars, based on 6 article reviews
    bax channel blocker - by Bioz Stars, 2026-03
    92/100 stars

    Images



    Similar Products

    bax channel blocker bcb  (Tocris)
    96
    Tocris bax channel blocker bcb
    Yoda1 + TRAIL apoptotic pathway. (A) Yoda1 is able to activate Piezo1, a mechanosensitive ion channel, under static conditions. This leads to Ca 2+ influx and a signaling cascade that enhances TRAIL-induced permeabilization of the mitochondria, resulting in increased apoptosis. (B) GsMTx-4 inhibits Piezo1 and other mechanosensitive ion channels, decreasing Ca 2+ influx and the synergistic effects of Yoda1. (C) Calpeptin inhibits calpain, decreasing the effect of extracellular Ca 2+ and leading to increased cell viability following treatment. (D) <t>Bax</t> <t>channel</t> <t>blocker</t> <t>(BCB)</t> inhibits Bax, blocking the effects of both Yoda1 and TRAIL, largely increasing cell viability.
    Bax Channel Blocker Bcb, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bax channel blocker bcb/product/Tocris
    Average 96 stars, based on 1 article reviews
    bax channel blocker bcb - by Bioz Stars, 2026-03
    96/100 stars
    		  Buy from Supplier
    bax channel blocker  (Santa Cruz Biotechnology)
    92
    Santa Cruz Biotechnology bax channel blocker
    Yoda1 + TRAIL apoptotic pathway. (A) Yoda1 is able to activate Piezo1, a mechanosensitive ion channel, under static conditions. This leads to Ca 2+ influx and a signaling cascade that enhances TRAIL-induced permeabilization of the mitochondria, resulting in increased apoptosis. (B) GsMTx-4 inhibits Piezo1 and other mechanosensitive ion channels, decreasing Ca 2+ influx and the synergistic effects of Yoda1. (C) Calpeptin inhibits calpain, decreasing the effect of extracellular Ca 2+ and leading to increased cell viability following treatment. (D) <t>Bax</t> <t>channel</t> <t>blocker</t> <t>(BCB)</t> inhibits Bax, blocking the effects of both Yoda1 and TRAIL, largely increasing cell viability.
    Bax Channel Blocker, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bax channel blocker/product/Santa Cruz Biotechnology
    Average 92 stars, based on 1 article reviews
    bax channel blocker - by Bioz Stars, 2026-03
    92/100 stars
    		  Buy from Supplier
    bax channel blocker 2160  (Tocris)
    90
    Tocris bax channel blocker 2160

    Bax Channel Blocker 2160, supplied by Tocris, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bax channel blocker 2160/product/Tocris
    Average 90 stars, based on 1 article reviews
    bax channel blocker 2160 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    bcl-2 associated x (bax) channel blocker bcb #a4459  (ApexBio)
    90
    ApexBio bcl-2 associated x (bax) channel blocker bcb #a4459

    Bcl 2 Associated X (Bax) Channel Blocker Bcb #A4459, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bcl-2 associated x (bax) channel blocker bcb #a4459/product/ApexBio
    Average 90 stars, based on 1 article reviews
    bcl-2 associated x (bax) channel blocker bcb #a4459 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    bcl-2 associated x (bax) channel blocker (bcb; #a4459)  (ApexBio)
    90
    ApexBio bcl-2 associated x (bax) channel blocker (bcb; #a4459)

    Bcl 2 Associated X (Bax) Channel Blocker (Bcb; #A4459), supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bcl-2 associated x (bax) channel blocker (bcb; #a4459)/product/ApexBio
    Average 90 stars, based on 1 article reviews
    bcl-2 associated x (bax) channel blocker (bcb; #a4459) - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    bax channel blocker (bcb)  (Tocris)
    90
    Tocris bax channel blocker (bcb)

    Bax Channel Blocker (Bcb), supplied by Tocris, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bax channel blocker (bcb)/product/Tocris
    Average 90 stars, based on 1 article reviews
    bax channel blocker (bcb) - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    bax channel blocker 77 1 nsc  (Tocris)
    94
    Tocris bax channel blocker 77 1 nsc

    Bax Channel Blocker 77 1 Nsc, supplied by Tocris, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bax channel blocker 77 1 nsc/product/Tocris
    Average 94 stars, based on 1 article reviews
    bax channel blocker 77 1 nsc - by Bioz Stars, 2026-03
    94/100 stars
    		  Buy from Supplier
    bax channel blocker  (Millipore)
    90
    Millipore bax channel blocker

    Bax Channel Blocker, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bax channel blocker/product/Millipore
    Average 90 stars, based on 1 article reviews
    bax channel blocker - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    bax channel blocker  (Tocris)
    93
    Tocris bax channel blocker

    Bax Channel Blocker, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bax channel blocker/product/Tocris
    Average 93 stars, based on 1 article reviews
    bax channel blocker - by Bioz Stars, 2026-03
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Yoda1 + TRAIL apoptotic pathway. (A) Yoda1 is able to activate Piezo1, a mechanosensitive ion channel, under static conditions. This leads to Ca 2+ influx and a signaling cascade that enhances TRAIL-induced permeabilization of the mitochondria, resulting in increased apoptosis. (B) GsMTx-4 inhibits Piezo1 and other mechanosensitive ion channels, decreasing Ca 2+ influx and the synergistic effects of Yoda1. (C) Calpeptin inhibits calpain, decreasing the effect of extracellular Ca 2+ and leading to increased cell viability following treatment. (D) Bax channel blocker (BCB) inhibits Bax, blocking the effects of both Yoda1 and TRAIL, largely increasing cell viability.

    Journal: ACS Omega

    Article Title: Chemical Activation and Mechanical Sensitization of Piezo1 Enhance TRAIL-Mediated Apoptosis in Glioblastoma Cells

    doi: 10.1021/acsomega.3c00705

    Figure Lengend Snippet: Yoda1 + TRAIL apoptotic pathway. (A) Yoda1 is able to activate Piezo1, a mechanosensitive ion channel, under static conditions. This leads to Ca 2+ influx and a signaling cascade that enhances TRAIL-induced permeabilization of the mitochondria, resulting in increased apoptosis. (B) GsMTx-4 inhibits Piezo1 and other mechanosensitive ion channels, decreasing Ca 2+ influx and the synergistic effects of Yoda1. (C) Calpeptin inhibits calpain, decreasing the effect of extracellular Ca 2+ and leading to increased cell viability following treatment. (D) Bax channel blocker (BCB) inhibits Bax, blocking the effects of both Yoda1 and TRAIL, largely increasing cell viability.

    Article Snippet: Yoda1, Calpeptin, and Bax channel blocker (BCB) were obtained from Tocris Bioscience (Bristol, United Kingdom).

    Techniques: Blocking Assay

    Cell viability after inhibition of the Yoda1 + TRAIL apoptotic pathway. (A) The effect of GsMTx-4 on Piezo1 represented by the normalized Ca 2+ influx in GBM cells following GsMTX-4 inhibition. (B) The effect of calpeptin (Calp) on the Yoda1 + TRAIL apoptotic pathway represented via GBM mitochondrial depolarization. (C) The effect of BCB on the Yoda1 + TRAIL apoptotic pathway represented via GBM mitochondrial depolarization. No significance (ns), * p < 0.05, ** p < 0.01, *** p < 0.005, **** p < 0.001.

    Journal: ACS Omega

    Article Title: Chemical Activation and Mechanical Sensitization of Piezo1 Enhance TRAIL-Mediated Apoptosis in Glioblastoma Cells

    doi: 10.1021/acsomega.3c00705

    Figure Lengend Snippet: Cell viability after inhibition of the Yoda1 + TRAIL apoptotic pathway. (A) The effect of GsMTx-4 on Piezo1 represented by the normalized Ca 2+ influx in GBM cells following GsMTX-4 inhibition. (B) The effect of calpeptin (Calp) on the Yoda1 + TRAIL apoptotic pathway represented via GBM mitochondrial depolarization. (C) The effect of BCB on the Yoda1 + TRAIL apoptotic pathway represented via GBM mitochondrial depolarization. No significance (ns), * p < 0.05, ** p < 0.01, *** p < 0.005, **** p < 0.001.

    Article Snippet: Yoda1, Calpeptin, and Bax channel blocker (BCB) were obtained from Tocris Bioscience (Bristol, United Kingdom).

    Techniques: Inhibition

    Journal: iScience

    Article Title: Development of novel cytoprotective small compounds inhibiting mitochondria-dependent cell death

    doi: 10.1016/j.isci.2023.107916

    Figure Lengend Snippet:

    Article Snippet: Bax Channle Blocker , Tocris , No. 2160.

    Techniques: Labeling, Recombinant, Software